Episode 5: Tesamorelin vs. Ipamorelin | Peptides for Growth Hormone, Fat Loss, and Better Sleep
Description
Welcome back to the Peptides for Women podcast, my little 80s babes!
Today we’re digging into two of the most fascinating (and fun to say!) peptides: Tesamorelin and Ipamorelin.
Both of these peptides help your body make more growth hormone, which naturally declines in your 30s, 40s, and 50s. And since growth hormone is the secret sauce for lean muscle, fat loss, skin, sleep, and recovery, this is a conversation you don’t want to miss.
In this episode, I break down:
What tesamorelin and ipamorelin actually do in your body (and how they’re different)
Why tesamorelin is especially powerful for midlife belly fat and body composition
The “thermostat vs. tap” analogy to help you understand their unique roles
How ipamorelin supports deep sleep, recovery, and mood—without messing with other hormones
What the research really says about fat loss, muscle, and brain health
How these peptides can be used together for even better results
The importance of healthy foundations (protein, lifting, sleep, sun, steps) before adding peptides
I’ll also share why I’m personally so excited to add tesamorelin into my own peptide stack, plus a few stories from clients and from my husband, Beau, who’s already seen incredible results with sermorelin.
📘 Resources Mentioned:
1. Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial
https://pubmed.ncbi.nlm.nih.gov/25038357/
2. Effects of Tesamorelin on Neurocognitive Impairment in Persons With HIV and Abdominal Obesity
https://pubmed.ncbi.nlm.nih.gov/39813152/
3. Tesamorelin Modestly Reduces Liver Fat
https://www.jwatch.org/na35376/2014/08/08/tesamorelin-modestly-reduces-liver-fat
4. Ipamorelin, the first selective growth hormone secretagogue
https://pubmed.ncbi.nlm.nih.gov/9849822/
5. The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats
https://pubmed.ncbi.nlm.nih.gov/10828840/
6. The role of peptides in bone healing and regeneration: a systematic review
https://pmc.ncbi.nlm.nih.gov/articles/PMC4940902/
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